CHRDL2 anticorps

N° du produit ABIN7238816

Détail du produit anti-CHRDL2 anticorps

Antigène: CHRDL2 (Chordin-Like 2 (CHRDL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRDL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human CHRDL2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CHRDL2

Antigène: CHRDL2 (Chordin-Like 2 (CHRDL2))

Autre désignation: CHRDL2 (CHRDL2 Produits)

Synonymes: anticorps BNF1, anticorps CHL2, anticorps FKSG37, anticorps 1810022C01Rik, anticorps Chl2, anticorps chl, anticorps si:dkey-11j5.7, anticorps si:dkey-11j5.7-like, anticorps chordin like 2, anticorps chordin-like 2, anticorps CHRDL2, anticorps Chrdl2, anticorps chrdl2

Sujet: CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.

Poids moléculaire: 48 kDa

NCBI Accession: NP_056239

UniProt: Q6WN34