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CHRDL2 anticorps

CHRDL2 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7238816
  • Antigène Voir toutes CHRDL2 Anticorps
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    Reactivité
    • 17
    • 16
    • 13
    • 1
    Humain
    Hôte
    • 28
    • 1
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHRDL2 est non-conjugé
    Application
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human CHRDL2
    Isotype
    IgG
    Top Product
    Discover our top product CHRDL2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    Autre désignation
    CHRDL2 (CHRDL2 Produits)
    Synonymes
    anticorps BNF1, anticorps CHL2, anticorps FKSG37, anticorps 1810022C01Rik, anticorps Chl2, anticorps chl, anticorps si:dkey-11j5.7, anticorps si:dkey-11j5.7-like, anticorps chordin like 2, anticorps chordin-like 2, anticorps CHRDL2, anticorps Chrdl2, anticorps chrdl2
    Sujet
    CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.
    Poids moléculaire
    48 kDa
    NCBI Accession
    NP_056239
    UniProt
    Q6WN34
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