CDK12 anticorps

N° du produit ABIN7001259

Détail du produit anti-CDK12 anticorps

Antigène: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK12 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human CDK12

Isotype: IgG

Information d'application

Indications d'application: IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CDK12

Antigène: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Autre désignation: CDK12 (CRKRS Produits)

Synonymes: anticorps AC017581, anticorps CG7597, anticorps Dmel\\CG7597, anticorps anon-WO0140519.165, anticorps cg7597, anticorps dCDK12, anticorps gi24668141, anticorps CRK7, anticorps CRKR, anticorps CRKRS, anticorps hCDK12, anticorps 1810022J16Rik, anticorps AI646528, anticorps Crk7, anticorps Crkrs, anticorps D11Ertd752e, anticorps Pksc, anticorps Cyclin-dependent kinase 12, anticorps cyclin dependent kinase 12, anticorps cyclin-dependent kinase 12, anticorps Cdk12, anticorps CDK12

Sujet: CrkRS (Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR) is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89 % identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 (cholinesterase-related cell division controller), however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.

NCBI Accession: NP_057591

UniProt: Q9NYV4