MT-ND1 anticorps

N° du produit ABIN7239224

Détail du produit anti-MT-ND1 anticorps

Antigène: MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MT-ND1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human MT-ND1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MT-ND1

Antigène: MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))

Autre désignation: MT-ND1 (MT-ND1 Produits)

Synonymes: anticorps MTND1, anticorps NADH1, anticorps MT-ND1, anticorps ND1, anticorps cypA, anticorps NADH dehydrogenase, subunit 1 (complex I), anticorps NADH dehydrogenase subunit 1, anticorps peptidylprolyl isomerase A, anticorps NADH dehydrogenasesubunit 1, anticorps mitochondrial NADH-ubiquinone oxidoreductase chain 1, anticorps ND1, anticorps PPIA, anticorps nad1, anticorps mt:ND1

Sujet: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

Poids moléculaire: 36 kDa

NCBI Accession: YP_003024026

UniProt: P03886