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HIF1AN anticorps

HIF1AN Reactivité: Humain, Souris WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7239416
  • Antigène Voir toutes HIF1AN Anticorps
    HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
    Reactivité
    • 82
    • 30
    • 20
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    Humain, Souris
    Hôte
    • 73
    • 7
    Lapin
    Clonalité
    • 66
    • 16
    Polyclonal
    Conjugué
    • 44
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HIF1AN est non-conjugé
    Application
    • 45
    • 25
    • 14
    • 14
    • 12
    • 12
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human HIF1AN
    Isotype
    IgG
    Top Product
    Discover our top product HIF1AN Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
    Autre désignation
    HIF1AN (HIF1AN Produits)
    Synonymes
    anticorps FIH1, anticorps 2310046M24Rik, anticorps A830014H24Rik, anticorps cb728, anticorps id:ibd5139, anticorps hypoxia inducible factor 1 alpha subunit inhibitor, anticorps hypoxia-inducible factor 1, alpha subunit inhibitor, anticorps hypoxia inducible factor 1, alpha subunit inhibitor, anticorps hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog, anticorps HIF1AN, anticorps Hif1an, anticorps hif1an, anticorps hif1an.S
    Sujet
    Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
    Poids moléculaire
    40 kDa
    NCBI Accession
    NP_060372
    UniProt
    Q9NWT6
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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