SLIT2 anticorps

N° du produit ABIN7239467

Détail du produit anti-SLIT2 anticorps

Antigène: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLIT2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SLIT2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLIT2

Antigène: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Autre désignation: SLIT2 (SLIT2 Produits)

Synonymes: anticorps SLIL3, anticorps Slit-2, anticorps Drad-1, anticorps E030015M03Rik, anticorps E130320P19Rik, anticorps Slil3, anticorps mKIAA4141, anticorps Slit, anticorps slil3, anticorps slit-2, anticorps slit2-a, anticorps SLIT2, anticorps slit guidance ligand 2, anticorps slit homolog 2 (Drosophila), anticorps slit guidance ligand 2 S homeolog, anticorps SLIT2, anticorps Slit2, anticorps slit2, anticorps slit2.S

Sujet: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

Poids moléculaire: 170 kDa

NCBI Accession: NP_004778

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration