Kallikrein 7 anticorps

N° du produit ABIN7240058

Détail du produit anti-Kallikrein 7 anticorps

Antigène: Kallikrein 7 (KLK7)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human KLK7

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: KLK7 (KLK7 Produits)

Synonymes: anticorps Prss6, anticorps SCCE, anticorps PRSS6, anticorps hK7, anticorps kallikrein related-peptidase 7 (chymotryptic, stratum corneum), anticorps kallikrein-related peptidase 7, anticorps kallikrein related peptidase 7, anticorps Klk7, anticorps KLK7

Sujet: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Poids moléculaire: 28 kDa

UniProt: P49862

Pathways: Système du Complément