anticorps ABCB6, anticorps abcb6, anticorps ABC, anticorps ABC14, anticorps LAN, anticorps MCOPCB7, anticorps MTABC3, anticorps PRP, anticorps umat, anticorps 1200005B17Rik, anticorps ATP binding cassette subfamily B member 6 (Langereis blood group), anticorps ATP binding cassette subfamily B member 6, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 6a, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 6, anticorps ABCB6, anticorps abcb6a, anticorps abcb6, anticorps Abcb6
Sujet
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.