STK40 anticorps

N° du produit ABIN7240700

Détail du produit anti-STK40 anticorps

Antigène: STK40 (serine/threonine Kinase 40 (STK40))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK40 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human STK40

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur STK40

Antigène: STK40 (serine/threonine Kinase 40 (STK40))

Autre désignation: STK40 (STK40 Produits)

Synonymes: anticorps cb988, anticorps fd99h11, anticorps wu:fd99h11, anticorps NV14115, anticorps DKFZp459J1924, anticorps RP11-268J15.4, anticorps SHIK, anticorps SgK495, anticorps 2310004N11Rik, anticorps AI428792, anticorps Lyk4, anticorps RGD1307310, anticorps serine/threonine kinase 40, anticorps serine/threonine kinase 40 L homeolog, anticorps STK40, anticorps stk40, anticorps LOC100123745, anticorps Stk40, anticorps stk40.L

Sujet: STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

UniProt: Q8N2I9