LTB anticorps

N° du produit ABIN7240826

Détail du produit anti-LTB anticorps

Antigène: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LTB est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human LTB

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LTB

Antigène: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Autre désignation: LTB (LTB Produits)

Synonymes: anticorps AI662801, anticorps LTbeta, anticorps Tnfc, anticorps Tnfsf3, anticorps p33, anticorps TNFC, anticorps TNFSF3, anticorps LT-b, anticorps LT-beta, anticorps TNF-C, anticorps lymphotoxin B, anticorps lymphotoxin beta, anticorps Ltb, anticorps LTB

Sujet: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI Accession: NP_002332

UniProt: Q06643

Pathways: Signalisation NF-kappaB