EID1 anticorps
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- Antigène Voir toutes EID1 Anticorps
- EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EID1 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human EID1
- Isotype
- IgG
- Top Product
- Discover our top product EID1 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.6 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))
- Autre désignation
- EID1 (EID1 Produits)
- Synonymes
- anticorps C15orf3, anticorps CRI1, anticorps EID-1, anticorps IRO45620, anticorps PTD014, anticorps RBP21, anticorps 2610002K20Rik, anticorps Cri1, anticorps ORF12, anticorps PNAS-22, anticorps RGD1562702, anticorps EP300 interacting inhibitor of differentiation 1, anticorps EID1, anticorps Eid1
- Sujet
- E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
- NCBI Accession
- NP_055150
- UniProt
- Q9Y6B2
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