KIF1C anticorps

N° du produit ABIN7241606

Détail du produit anti-KIF1C anticorps

Antigène: KIF1C (Kinesin Family Member 1C (KIF1C))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF1C est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human KIF1C

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KIF1C

Antigène: KIF1C (Kinesin Family Member 1C (KIF1C))

Autre désignation: KIF1C (KIF1C Produits)

Synonymes: anticorps KIF1C, anticorps ltxs1, anticorps DKFZp468E0822, anticorps LTXS1, anticorps B430105J22Rik, anticorps D11Bwg1349e, anticorps Ltxs1, anticorps kinesin family member 1C, anticorps KIF1C, anticorps kif1c, anticorps Kif1c

Sujet: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis . KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons . Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle . Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta . In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.

Poids moléculaire: 123 kDa

UniProt: O43896