anticorps AV260376, anticorps IASPP, anticorps Nkip1, anticorps wa3, anticorps zgc:113058, anticorps NKIP1, anticorps RAI, anticorps RAI4, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 13 like, anticorps protein phosphatase 1, regulatory subunit 13 like, anticorps protein phosphatase 1 regulatory subunit 13 like, anticorps protein phosphatase 1 regulatory subunit 13 like L homeolog, anticorps Ppp1r13l, anticorps ppp1r13l, anticorps PPP1R13L, anticorps ppp1r13l.L
Sujet
RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.