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MCM4 anticorps

MCM4 Reactivité: Humain, Souris WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7242281
  • Antigène Voir toutes MCM4 Anticorps
    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
    Reactivité
    • 80
    • 35
    • 22
    • 10
    • 10
    • 10
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    Humain, Souris
    Hôte
    • 74
    • 4
    • 3
    Lapin
    Clonalité
    • 79
    • 2
    Polyclonal
    Conjugué
    • 51
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MCM4 est non-conjugé
    Application
    • 66
    • 30
    • 30
    • 13
    • 13
    • 13
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human MCM4
    Isotype
    IgG
    Top Product
    Discover our top product MCM4 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
    Autre désignation
    MCM4 (MCM4 Produits)
    Sujet
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
    Poids moléculaire
    97 kDa
    NCBI Accession
    NP_877423
    UniProt
    P33991
    Pathways
    Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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