RRAD anticorps

N° du produit ABIN7242650

Détail du produit anti-RRAD anticorps

Antigène: RRAD (Ras-Related Associated with Diabetes (RRAD))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRAD est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human RRAD

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RRAD

Antigène: RRAD (Ras-Related Associated with Diabetes (RRAD))

Autre désignation: RRAD (RRAD Produits)

Synonymes: anticorps ZGC:63471, anticorps RRAD, anticorps RAD, anticorps RAD1, anticorps REM3, anticorps Rad, anticorps RRAD, Ras related glycolysis inhibitor and calcium channel regulator, anticorps Ras-related associated with diabetes, anticorps RRAD, anticorps Rrad

Sujet: The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.

NCBI Accession: NP_004156

UniProt: P55042