anticorps A2AP, anticorps AAP, anticorps ALPHA-2-PI, anticorps API, anticorps PLI, anticorps serpin, anticorps AI747498, anticorps Pli, anticorps Serpimf2, anticorps serpinf2, anticorps serpinf2l, anticorps wu:fd57d08, anticorps Dmrs91, anticorps Pedf, anticorps serpin family F member 2, anticorps serpin family F member 1, anticorps serine (or cysteine) peptidase inhibitor, clade F, member 2, anticorps serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a, anticorps SERPINF2, anticorps Serpinf2, anticorps SERPINF1, anticorps serpinf2a, anticorps Serpinf1
Sujet
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.