ARHGEF11 anticorps

N° du produit ABIN7242893

Détail du produit anti-ARHGEF11 anticorps

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF11 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human ARHGEF11

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARHGEF11

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Autre désignation: ARHGEF11 (ARHGEF11 Produits)

Synonymes: anticorps ARHGEF11, anticorps GTRAP48, anticorps PDZ-RHOGEF, anticorps B930073M02, anticorps E130307F09, anticorps PDZ-RhoGEF, anticorps Prg, anticorps RhoGEF, anticorps mKIAA0380, anticorps Gtrap48, anticorps Rho guanine nucleotide exchange factor (GEF) 11, anticorps Rho guanine nucleotide exchange factor 11, anticorps rho guanine nucleotide exchange factor 11, anticorps arhgef11, anticorps ARHGEF11, anticorps Arhgef11, anticorps LOC511220

Sujet: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Poids moléculaire: 168 kDa

NCBI Accession: NP_055599

UniProt: O15085

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling