RCAN1 anticorps

N° du produit ABIN7242911

Détail du produit anti-RCAN1 anticorps

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCAN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human RCAN1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RCAN1

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Autre désignation: DSCR1 (RCAN1 Produits)

Synonymes: anticorps ADAPT78, anticorps CSP1, anticorps DSC1, anticorps DSCR1, anticorps MCIP1, anticorps RCN1, anticorps RCAN1, anticorps 2410048A02Rik, anticorps AA408855, anticorps AI429645, anticorps AL024459, anticorps AV028423, anticorps Adapt78, anticorps CALP1L, anticorps Dscr1, anticorps Mcip1, anticorps dscr1, anticorps rcan1, anticorps wu:fr92c05, anticorps adapt78, anticorps csp1, anticorps dsc1, anticorps mcip1, anticorps MGC53636, anticorps rcn1, anticorps MGC69428, anticorps regulator of calcineurin 1, anticorps regulator of calcineurin 1b, anticorps regulator of calcineurin 1 L homeolog, anticorps Down syndrome critical region gene 1, anticorps RCAN1, anticorps Rcan1, anticorps rcan1b, anticorps rcan1.L, anticorps dscr1, anticorps rcan1

Sujet: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Poids moléculaire: 28 kDa

NCBI Accession: NP_004405

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development