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B-Cell Linker anticorps

BLNK Reactivité: Humain, Souris, Rat ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7243052
  • Antigène Voir toutes B-Cell Linker (BLNK) Anticorps
    B-Cell Linker (BLNK)
    Reactivité
    • 114
    • 79
    • 43
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 117
    • 15
    • 1
    Lapin
    Clonalité
    • 118
    • 15
    Polyclonal
    Conjugué
    • 50
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp B-Cell Linker est non-conjugé
    Application
    • 110
    • 52
    • 34
    • 26
    • 20
    • 19
    • 17
    • 8
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Synthetic peptide of human BLNK
    Isotype
    IgG
    Top Product
    Discover our top product BLNK Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    B-Cell Linker (BLNK)
    Autre désignation
    BLNK (BLNK Produits)
    Synonymes
    anticorps BLNK, anticorps blnk, anticorps MGC147045, anticorps BASH, anticorps Bca, anticorps Ly-57, anticorps Ly57, anticorps Lyw-57, anticorps SLP-65, anticorps AGM4, anticorps BLNK-S, anticorps LY57, anticorps SLP65, anticorps bca, anticorps B-cell linker, anticorps B cell linker, anticorps BLNK, anticorps blnk, anticorps Blnk
    Sujet
    This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.
    Poids moléculaire
    50 kDa
    NCBI Accession
    NP_001107566
    UniProt
    Q8WV28
    Pathways
    BCR Signaling
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