DEAF1 anticorps

N° du produit ABIN7243235

Détail du produit anti-DEAF1 anticorps

Antigène: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEAF1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human DEAF1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DEAF1

Antigène: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Autre désignation: DEAF1 (DEAF1 Produits)

Synonymes: anticorps AU042387, anticorps C230009B13Rik, anticorps NUDR, anticorps SPN, anticorps ZMYND5, anticorps MYND5, anticorps spn, anticorps DEAF1, anticorps nudr, anticorps zmynd5, anticorps CG8567, anticorps DEAF-1, anticorps Deaf-1, anticorps Dmel\\CG8567, anticorps deaf1, anticorps l(3)76BDv, anticorps deformed epidermal autoregulatory factor 1 (Drosophila), anticorps DEAF1, transcription factor, anticorps DEAF1 transcription factor, anticorps deformed epidermal autoregulatory factor 1 homolog, anticorps Deformed epidermal autoregulatory factor-1, anticorps Deaf1, anticorps DEAF1, anticorps LOC509260, anticorps deaf1, anticorps deaf-1

Sujet: Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.

NCBI Accession: NP_066288

UniProt: O75398

Pathways: Tube Formation