MAL anticorps

N° du produit ABIN7243547

Détail du produit anti-MAL anticorps

Antigène: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAL est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human MAL

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MAL

Antigène: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Autre désignation: MAL (MAL Produits)

Synonymes: anticorps AI326936, anticorps Bp50, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps p50, anticorps Mpv17, anticorps Vip17, anticorps mal, anticorps wyatt, anticorps MALGENE, anticorps im:7142606, anticorps zgc:112003, anticorps mal, T-cell differentiation protein, anticorps CD40 antigen, anticorps myelin and lymphocyte protein, T cell differentiation protein, anticorps myelin and lymphocyte protein, anticorps toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog, anticorps MAL, anticorps Cd40, anticorps Mal, anticorps LOC100135389, anticorps mal, anticorps tirap.L

Sujet: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

NCBI Accession: NP_002362

UniProt: P21145

Pathways: Asymmetric Protein Localization