TTI1 anticorps

N° du produit ABIN7244333

Détail du produit anti-TTI1 anticorps

Antigène: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTI1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human TTI1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TTI1

Antigène: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Autre désignation: TTI1 (TTI1 Produits)

Synonymes: anticorps KIAA0406, anticorps smg-10, anticorps 2610036D13Rik, anticorps AI449463, anticorps RGD1562582, anticorps TELO2 interacting protein 1, anticorps TTI1, anticorps Tti1

Sujet: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

NCBI Accession: NP_055472

UniProt: O43156