EPS15 anticorps

N° du produit ABIN7244873

Détail du produit anti-EPS15 anticorps

Antigène: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPS15 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human EPS15

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EPS15

Antigène: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Autre désignation: EPS15 (EPS15 Produits)

Synonymes: anticorps AF-1P, anticorps AF1P, anticorps MLLT5, anticorps CG16932, anticorps Dmel\\CG16932, anticorps EH1, anticorps EPS-15, anticorps Eps15, anticorps anon-WO0118547.85, anticorps eps-15, anticorps eps15, anticorps i31, anticorps 2410112D09Rik, anticorps RGD1307641, anticorps epidermal growth factor receptor pathway substrate 15, anticorps Epidermal growth factor receptor pathway substrate clone 15, anticorps hypothetical protein, anticorps EPS15, anticorps Eps-15, anticorps eps15, anticorps Eps15, anticorps PGTG_06574

Sujet: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15) is a Protein Coding gene. Diseases associated with EPS15 include Vaccinia. Among its related pathways are Notch signaling pathway (KEGG) and HIV Life Cycle. GO annotations related to this gene include calcium ion binding and SH3 domain binding. An important paralog of this gene is EPS15L1.

UniProt: P42566

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation