KDM2A anticorps

N° du produit ABIN7244933

Détail du produit anti-KDM2A anticorps

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM2A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human KDM2A

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.62 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KDM2A

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Autre désignation: KDM2A (KDM2A Produits)

Synonymes: anticorps FBXL11, anticorps JHDM1A, anticorps 100043628, anticorps 5530401A10Rik, anticorps AA589516, anticorps AW536790, anticorps Cxxc8, anticorps Fbl11, anticorps Fbl7, anticorps Fbxl11, anticorps Gm4560, anticorps Jhdm1, anticorps Jhdm1a, anticorps lalina, anticorps KDM2A, anticorps CXXC8, anticorps FBL11, anticorps FBL7, anticorps LILINA, anticorps fb76b11, anticorps wu:fb76b11, anticorps wu:fj11c04, anticorps zgc:158441, anticorps zgc:158606, anticorps lysine demethylase 2A, anticorps lysine (K)-specific demethylase 2A, anticorps lysine (K)-specific demethylase 2Aa, anticorps KDM2A, anticorps Kdm2a, anticorps kdm2aa

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.

UniProt: Q9Y2K7

Pathways: L'effet Warburg