GFI1B anticorps

N° du produit ABIN7245053

Détail du produit anti-GFI1B anticorps

Antigène: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFI1B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human GFI1B

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GFI1B

Antigène: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Autre désignation: GFI1B (GFI1B Produits)

Synonymes: anticorps GFI1B, anticorps GFI, anticorps znf544, anticorps MGC80648, anticorps Gfi-1B, anticorps growth factor independent 1B transcriptional repressor, anticorps growth factor independent 1B transcription repressor L homeolog, anticorps Zinc finger protein Gfi-1b, anticorps growth factor independent 1B, anticorps GFI1B, anticorps Gfi1b, anticorps gfi1b.L, anticorps gfi1b

Sujet: This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.GFI1B (Growth Factor Independent 1B Transcriptional Repressor) is a Protein Coding gene. Diseases associated with GFI1B include Bleeding Disorder, Platelet-Type, 17 and Gray Platelet Syndrome. Among its related pathways are NF-kappaB Signaling. GO annotations related to this gene include RNA polymerase II transcription factor binding. An important paralog of this gene is GFI1.

UniProt: Q5VTD9

Pathways: Cellular Response to Molecule of Bacterial Origin