JIP3 anticorps

N° du produit ABIN7245380

Détail du produit anti-JIP3 anticorps

Antigène: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JIP3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human MAPK8IP3

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.26 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur JIP3

Antigène: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Autre désignation: MAPK8IP3 (MAPK8IP3 Produits)

Synonymes: anticorps JIP3, anticorps JSAP1, anticorps SYD2, anticorps syd, anticorps BB120594, anticorps D17Wsu15e, anticorps JIP-3, anticorps JSAP1a, anticorps JSAP1b, anticorps JSAP1c, anticorps JSAP1d, anticorps Jip3, anticorps Syd2, anticorps mKIAA1066, anticorps mitogen-activated protein kinase 8 interacting protein 3, anticorps MAPK8IP3, anticorps mapk8ip3, anticorps Mapk8ip3

Sujet: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. MAPK8IP3 (Mitogen-Activated Protein Kinase 8 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are MAPK signaling pathway and Arf6 trafficking events. GO annotations related to this gene include kinesin binding and receptor signaling complex scaffold activity. An important paralog of this gene is SPAG9.

UniProt: Q9UPT6