BAG3 anticorps

N° du produit ABIN7245527

Détail du produit anti-BAG3 anticorps

Antigène: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human BAG3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BAG3

Antigène: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Autre désignation: BAG3 (BAG3 Produits)

Synonymes: anticorps bag3-A, anticorps MGC53113, anticorps zgc:100859, anticorps BAG3, anticorps ATBAG3, anticorps BCL-2-associated athanogene 3, anticorps T28J14.160, anticorps T28J14_160, anticorps BAG-3, anticorps BIS, anticorps CAIR-1, anticorps MFM6, anticorps AA407278, anticorps Bis, anticorps mg638, anticorps BCL2 associated athanogene 3 L homeolog, anticorps BCL2-associated athanogene 3, anticorps BCL2 associated athanogene 3, anticorps BCL-2-associated athanogene 3, anticorps Bcl2-associated athanogene 3, anticorps bag3.L, anticorps bag3, anticorps BAG3, anticorps Bag3

Sujet: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 62 kDa

UniProt: O95817