Tppp anticorps
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- Antigène Voir toutes Tppp Anticorps
- Tppp (Tubulin Polymerization Promoting Protein (Tppp))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Tppp est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Full length fusion protein
- Isotype
- IgG
- Top Product
- Discover our top product Tppp Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.8 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Tppp (Tubulin Polymerization Promoting Protein (Tppp))
- Autre désignation
- TPPP (Tppp Produits)
- Synonymes
- anticorps TPPP/p25, anticorps TPPP1, anticorps p24, anticorps p25, anticorps p25alpha, anticorps 2900041A09Rik, anticorps AI849835, anticorps RGD1310121, anticorps tubulin polymerization promoting protein, anticorps TPPP, anticorps Tppp
- Sujet
- Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
- Poids moléculaire
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Observed_MW: Refer to figures
Calculated_MW: 24 kDa
- UniProt
- O94811
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