UNC45B anticorps

N° du produit ABIN7245968

Détail du produit anti-UNC45B anticorps

Antigène: UNC45B (Unc-45 Homolog B (UNC45B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC45B est non-conjugé

Application: ELISA, Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human UNC45B

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur UNC45B

Antigène: UNC45B (Unc-45 Homolog B (UNC45B))

Autre désignation: UNC45B (UNC45B Produits)

Synonymes: anticorps MGC80931, anticorps cmya4, anticorps AA445617, anticorps Cmya4, anticorps D230041A13Rik, anticorps Unc45, anticorps CMYA4, anticorps SMUNC45, anticorps UNC45, anticorps Unc-45B, anticorps cb393, anticorps unc45r, anticorps wu:fa05a03, anticorps wu:fa10f03, anticorps wu:fb37f02, anticorps wu:fb96f06, anticorps wu:fc10f04, anticorps unc-45 myosin chaperone B S homeolog, anticorps unc-45 myosin chaperone B, anticorps unc45b.S, anticorps unc45b, anticorps UNC45B, anticorps Unc45b

Sujet: This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 104/95 kDa

UniProt: Q8IWX7