PHF21A anticorps

N° du produit ABIN7246025

Détail du produit anti-PHF21A anticorps

Antigène: PHF21A (PHD Finger Protein 21A (PHF21A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHF21A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human PHF21A

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PHF21A

Antigène: PHF21A (PHD Finger Protein 21A (PHF21A))

Autre désignation: PHF21A (PHF21A Produits)

Synonymes: anticorps PHF21A, anticorps im:7138823, anticorps si:dkey-23n7.9, anticorps BHC80, anticorps RGD1560612, anticorps 80kDa, anticorps Bhc, anticorps Bhc80, anticorps D030065N23Rik, anticorps PFTF1, anticorps fj98d03, anticorps phf21a, anticorps wu:fj98d03, anticorps PHD finger protein 21A, anticorps PHD finger protein 21Aa, anticorps PHD finger protein 21Ab, anticorps PHF21A, anticorps phf21aa, anticorps pf21a, anticorps phf21a, anticorps LOC100549929, anticorps Phf21a, anticorps phf21ab

Sujet: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 75 kDa

UniProt: Q96BD5

Pathways: Feeding Behaviour