C1ORF106 anticorps

N° du produit ABIN7246082

Détail du produit anti-C1ORF106 anticorps

Antigène: C1ORF106 (Chromosome 1 Open Reading Frame 106 (C1ORF106))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1ORF106 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human C1orf106

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur C1ORF106

Antigène: C1ORF106 (Chromosome 1 Open Reading Frame 106 (C1ORF106))

Autre désignation: C1orf106 (C1ORF106 Produits)

Synonymes: anticorps chromosome 1 open reading frame 106, anticorps C1orf106

Sujet: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf106 gene product has been provisionally designated C1orf106 pending further characterization.

UniProt: Q3KP66