anticorps CALML5, anticorps CLSP, anticorps F14B2.33, anticorps multicopy suppressors of snf4 deficiency in yeast 3, anticorps calmodulin like 5, anticorps calmodulin-like 5, anticorps Calcium-binding EF-hand family protein, anticorps CALML5, anticorps MSS3
Sujet
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.