DENND1B anticorps

N° du produit ABIN7246211

Détail du produit anti-DENND1B anticorps

Antigène: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND1B est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human DENND1B

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.54 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DENND1B

Antigène: DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

Autre désignation: DENND1B (DENND1B Produits)

Synonymes: anticorps C1ORF18, anticorps C1orf218, anticorps FAM31B, anticorps 4632404N19Rik, anticorps 4930467M19Rik, anticorps 6820401H01Rik, anticorps F730008N07Rik, anticorps Fam31b, anticorps si:ch211-195i21.1, anticorps DENN domain containing 1B, anticorps DENN/MADD domain containing 1B, anticorps DENND1B, anticorps dennd1b, anticorps Dennd1b

Sujet: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 86 kDa

UniProt: Q6P3S1