PSMC4 anticorps
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- Antigène Voir toutes PSMC4 Anticorps
- PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PSMC4 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Fusion protein of human PSMC4
- Isotype
- IgG
- Top Product
- Discover our top product PSMC4 Anticorps primaire
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- Indications d'application
- IHC 1:30-1:150, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
- Autre désignation
- PSMC4 (PSMC4 Produits)
- Synonymes
- anticorps NCU02260.1, anticorps AO090003000692, anticorps DDBDRAFT_0188209, anticorps DDBDRAFT_0191435, anticorps DDB_0188209, anticorps DDB_0191435, anticorps MIP224, anticorps RPT3, anticorps S6, anticorps TBP-7, anticorps TBP7, anticorps CIP21, anticorps Tbp7, anticorps 26S protease regulatory subunit 6B, anticorps regulatory particle, ATPase-like-3, anticorps 26S proteasome regulatory subunit 6B, anticorps proteasome 26S subunit, ATPase 4, anticorps proteasome (prosome, macropain) 26S subunit, ATPase, 4, anticorps LOC732870, anticorps rpt-3, anticorps ATEG_04674, anticorps LELG_01296, anticorps HCAG_00039, anticorps LOC5568998, anticorps GL50803_7950, anticorps EDI_044950, anticorps AOR_1_1218154, anticorps PTRG_03339, anticorps psmC4, anticorps prs6b, anticorps LOC100381342, anticorps psmc4, anticorps PSMC4, anticorps Psmc4
- Sujet
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniProt
- P43686
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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