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NARF anticorps

NARF Reactivité: Humain, Souris, Rat ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7246325
  • Antigène Voir toutes NARF Anticorps
    NARF (Nuclear Prelamin A Recognition Factor (NARF))
    Reactivité
    • 35
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 50
    • 1
    Lapin
    Clonalité
    • 50
    • 1
    Polyclonal
    Conjugué
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NARF est non-conjugé
    Application
    • 40
    • 26
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Fusion protein of human NARF
    Isotype
    IgG
    Top Product
    Discover our top product NARF Anticorps primaire
  • Indications d'application
    IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.56 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    NARF (Nuclear Prelamin A Recognition Factor (NARF))
    Autre désignation
    NARF (NARF Produits)
    Synonymes
    anticorps NARF, anticorps IOP2, anticorps 4430402O11Rik, anticorps RGD1310894, anticorps wu:fa03c01, anticorps zgc:92186, anticorps nuclear prelamin A recognition factor, anticorps nuclear prelamin A recognition factor L homeolog, anticorps NARF, anticorps NAEGRDRAFT_78871, anticorps VDBG_04882, anticorps Tsp_07547, anticorps Tsp_07549, anticorps Narf, anticorps narf, anticorps narf.L
    Sujet
    Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.
    UniProt
    Q9UHQ1
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