anticorps im:7138234, anticorps wu:fb12b01, anticorps zgc:158151, anticorps 4732463H20Rik, anticorps HPIP, anticorps pre-B-cell leukemia homeobox interacting protein 1b, anticorps PBX homeobox interacting protein 1, anticorps pre B cell leukemia transcription factor interacting protein 1, anticorps pbxip1b, anticorps PBXIP1, anticorps Pbxip1
Sujet
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.