TIMM8A/DDP anticorps

N° du produit ABIN7246412

Détail du produit anti-TIMM8A/DDP anticorps

Antigène: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMM8A/DDP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human TIMM8A

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TIMM8A/DDP

Antigène: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Autre désignation: TIMM8A (TIMM8A Produits)

Synonymes: anticorps TIMM8A, anticorps ddp, anticorps tim8a, anticorps timm8a, anticorps DDP, anticorps DDP1, anticorps DFN1, anticorps MTS, anticorps TIM8, anticorps im:6896085, anticorps zgc:100916, anticorps Ddp1, anticorps Timm8a, anticorps DXHXS1274E, anticorps Fci-12, anticorps Tim8a, anticorps translocase of inner mitochondrial membrane 8 homolog A (yeast), anticorps translocase of inner mitochondrial membrane 8A, anticorps translocase of inner mitochondrial membrane 8 homolog A1 (yeast), anticorps translocase of inner mitochondrial membrane 8A1, anticorps TIMM8A, anticorps timm8a, anticorps Timm8a1

Sujet: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: O60220