PLGLB2 anticorps

N° du produit ABIN7246427

Détail du produit anti-PLGLB2 anticorps

Antigène: PLGLB2 (Plasminogen-Like B2 (PLGLB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLGLB2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human PLGLB2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLGLB2

Antigène: PLGLB2 (Plasminogen-Like B2 (PLGLB2))

Autre désignation: PLGLB2 (PLGLB2 Produits)

Synonymes: anticorps PLGP1, anticorps plasminogen-like B2, anticorps PLGLB2

Sujet: Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. PLGLB2 (plasminogen-like B2), also known as PLGP1, is a 96 amino acid protein that resembles the N-terminal plasminogen activation peptide, which is released from plasminogen during conversion to plasmin. PLGLB2 may bind to lysine binding sites present in the kringle structures of plasminogen, an event that interfers with the binding of fibrin or α-2 antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.

UniProt: Q02325