MGP anticorps

N° du produit ABIN7246430

Détail du produit anti-MGP anticorps

Antigène: MGP (Matrix Gla Protein (MGP))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human MGP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:70-1:350, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.32 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MGP

Antigène: MGP (Matrix Gla Protein (MGP))

Autre désignation: MGP (MGP Produits)

Synonymes: anticorps MGLAP, anticorps NTI, anticorps Mglap, anticorps mgp-A, anticorps MGP, anticorps LOC100136434, anticorps mgp, anticorps matrix Gla protein, anticorps matrix Gla protein L homeolog, anticorps MGP, anticorps Mgp, anticorps mgp.L, anticorps mgp

Sujet: Matrix Gla protein (MGP) is is a vitamin K-dependent,extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP),which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS),which is an autosomal recessive disorder characterized by abnormal cartilage calcification,peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.

UniProt: P08493