RNF111 anticorps

N° du produit ABIN7246457

Détail du produit anti-RNF111 anticorps

Antigène: RNF111 (Ring Finger Protein 111 (RNF111))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF111 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human RNF111

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RNF111

Antigène: RNF111 (Ring Finger Protein 111 (RNF111))

Autre désignation: RNF111 (RNF111 Produits)

Synonymes: anticorps ARK, anticorps Arkadia, anticorps RNF111, anticorps rnf111, anticorps ark, anticorps MGC81253, anticorps MGC146379, anticorps ring finger protein 111, anticorps ring finger 111, anticorps RNF111, anticorps Rnf111, anticorps rnf111-b, anticorps rnf111

Sujet: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

UniProt: Q6ZNA4