PSMD12 anticorps

N° du produit ABIN7246631

Détail du produit anti-PSMD12 anticorps

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human PSMD12

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PSMD12

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Autre désignation: PSMD12 (PSMD12 Produits)

Synonymes: anticorps wu:fb38a06, anticorps wu:fc34f08, anticorps wu:fc49f02, anticorps PSMD12, anticorps rpn5, anticorps Rpn5, anticorps p55, anticorps 1500002F15Rik, anticorps AI480719, anticorps P55, anticorps proteasome 26S subunit, non-ATPase 12, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 12, anticorps psmd12, anticorps PSMD12, anticorps Psmd12

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 53 kDa

UniProt: O00232

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway