IFITM2 anticorps

N° du produit ABIN7246760

Détail du produit anti-IFITM2 anticorps

Antigène: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFITM2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human IFITM2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IFITM2

Antigène: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Autre désignation: IFITM2 (IFITM2 Produits)

Synonymes: anticorps 1-8D, anticorps DSPA2c, anticorps Ifitm3l, anticorps fragilis3, anticorps mil-3, anticorps Ifitml, anticorps interferon induced transmembrane protein 2, anticorps IFITM2, anticorps Ifitm2

Sujet: IFITM2,also named as 1-8D,belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus (WNV),by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2.

UniProt: Q01629