GSKIP anticorps

N° du produit ABIN7246769

Détail du produit anti-GSKIP anticorps

Antigène: GSKIP (GSK3B interacting protein (GSKIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSKIP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human GSKIP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSKIP

Antigène: GSKIP (GSK3B interacting protein (GSKIP))

Autre désignation: GSKIP (GSKIP Produits)

Synonymes: anticorps C14orf129, anticorps 4933433P14Rik, anticorps RGD1308470, anticorps C21H14orf129, anticorps C8H14orf129, anticorps wu:fc74a11, anticorps wu:fd02b09, anticorps zgc:55683, anticorps c14orf129, anticorps gskip, anticorps GSK3B interacting protein, anticorps gsk3b interacting protein, anticorps GSK3B interacting protein L homeolog, anticorps GSKIP, anticorps Gskip, anticorps gskip, anticorps gskip.L

Sujet: This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

UniProt: Q9P0R6