DUSP7 anticorps

N° du produit ABIN7246991

Détail du produit anti-DUSP7 anticorps

Antigène: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP7 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human DUSP7

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP7

Antigène: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Autre désignation: DUSP7 (DUSP7 Produits)

Synonymes: anticorps DUSP7, anticorps mkpx, anticorps mkp-x, anticorps pyst2, anticorps MKPX, anticorps PYST2, anticorps AU015694, anticorps Mkpx, anticorps Pyst2, anticorps mkp-X, anticorps dual specificity phosphatase 7, anticorps Dual specificity protein phosphatase 7, anticorps DUSP7, anticorps dusp7, anticorps dus7, anticorps Dusp7

Sujet: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).

UniProt: Q16829

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades