anticorps 1190009B22, anticorps Jr2, anticorps [s]3A, anticorps zgc:101676, anticorps zgc:112172, anticorps ap1s3, anticorps adaptor-related protein complex AP-1, sigma 3, anticorps adaptor related protein complex 1 sigma 3 subunit, anticorps adaptor-related protein complex 1, sigma 3 subunit, b, anticorps adaptor-related protein complex 1, sigma 3 subunit, a, anticorps adaptor related protein complex 1 sigma 3 subunit S homeolog, anticorps Ap1s3, anticorps AP1S3, anticorps ap1s3b, anticorps ap1s3a, anticorps ap1s3.S
Sujet
This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.