DNAJA4 anticorps

N° du produit ABIN7247618

Détail du produit anti-DNAJA4 anticorps

Antigène: DNAJA4 (DnaJ (Hsp40) Homolog, Subfamily A, Member 4 (DNAJA4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human DNAJA4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DNAJA4

Antigène: DNAJA4 (DnaJ (Hsp40) Homolog, Subfamily A, Member 4 (DNAJA4))

Autre désignation: DNAJA4 (DNAJA4 Produits)

Synonymes: anticorps MGC52928, anticorps MST104, anticorps MSTP104, anticorps PRO1472, anticorps 1110021L12Rik, anticorps AV358213, anticorps Dj4, anticorps Hsj4, anticorps mmDjA4, anticorps DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog, anticorps DnaJ heat shock protein family (Hsp40) member A4, anticorps dnaja4.2.S, anticorps DNAJA4, anticorps Dnaja4

Sujet: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 45 kDa

UniProt: Q8WW22