DREAM anticorps

N° du produit ABIN7247663

Détail du produit anti-DREAM anticorps

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DREAM est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human KCNIP3

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.62 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DREAM

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Autre désignation: KCNIP3 (KCNIP3 Produits)

Synonymes: anticorps CSEN, anticorps DREAM, anticorps KCHIP3, anticorps 4933407H12Rik, anticorps AI413860, anticorps Csen, anticorps KChIP3, anticorps R74849, anticorps Dream, anticorps rKChIP3, anticorps csen, anticorps im:7145308, anticorps kcnip3, anticorps zgc:73306, anticorps KCNIP3, anticorps potassium voltage-gated channel interacting protein 3, anticorps Kv channel-interacting protein 4, anticorps calsenilin, anticorps Kv channel interacting protein 3, calsenilin, anticorps Kv channel interacting protein 3b, calsenilin, anticorps KCNIP3, anticorps LOC5568664, anticorps CpipJ_CPIJ002549, anticorps Tsp_05009, anticorps Kcnip3, anticorps kcnip3b, anticorps kcnip3

Sujet: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

UniProt: Q9Y2W7