SAV1 anticorps
-
- Antigène Voir toutes SAV1 Anticorps
- SAV1 (Salvador Homolog 1 (SAV1))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SAV1 est non-conjugé
-
Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Fusion protein of human SAV1
- Isotype
- IgG
- Top Product
- Discover our top product SAV1 Anticorps primaire
-
-
- Indications d'application
- IHC 1:100-1:300, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.32 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- SAV1 (Salvador Homolog 1 (SAV1))
- Autre désignation
- SAV1 (SAV1 Produits)
- Synonymes
- anticorps SAV, anticorps WW45, anticorps WWP4, anticorps 1700040G09Rik, anticorps Salv, anticorps Sav, anticorps Wwp3, anticorps Wwp4, anticorps salvador family WW domain containing protein 1, anticorps salvador family WW domain containing 1, anticorps SAV1, anticorps Sav1
- Sujet
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
- UniProt
- Q9H4B6
- Pathways
- Stem Cell Maintenance
-