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Cullin 4A anticorps

CUL4A Reactivité: Humain, Souris WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7247885
  • Antigène Voir toutes Cullin 4A (CUL4A) Anticorps
    Cullin 4A (CUL4A)
    Reactivité
    • 59
    • 27
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 53
    • 6
    Lapin
    Clonalité
    • 47
    • 12
    Polyclonal
    Conjugué
    • 31
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Cullin 4A est non-conjugé
    Application
    • 37
    • 24
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of human CUL4A
    Isotype
    IgG
    Top Product
    Discover our top product CUL4A Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.62 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Cullin 4A (CUL4A)
    Autre désignation
    CUL4A (CUL4A Produits)
    Synonymes
    anticorps zgc:64071, anticorps CUL4A, anticorps 2810470J21Rik, anticorps AW495282, anticorps RGD1563853, anticorps cullin 4A, anticorps CUL4A, anticorps cul4a, anticorps Cul4a
    Sujet
    Cullin proteins assemble a large number of RING E3 ubiquitin ligases,participating in the proteolysis through the ubiquitin-proteasome pathway. Two cullin 4 (CUL4) proteins,CUL4A (87 kDa) and CUL4B(104 kDa),have been identified. The two CUL4 sequences are 83 % identical. They target certain proteins for degradation by binding protein DDB1 to form a CUL4-DDB1 ubiquitin ligase complex with DDB. They form two individual E3 ligases,DDB1-CUL4ADDB2 and DDB1-CUL4BDDB2 in this process. CUL4A appeared in both the nucleus and the cytosol,suggesting a more complex mechanism for entering the nucleus. CUL4B is localized in the nucleus and facilitates the transfer of DDB1 into the nucleus independently of DDB2.
    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 88 kDa

    UniProt
    Q13619
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