anticorps AI037035, anticorps Tb03.48O8.160, anticorps zgc:103765, anticorps zgc:191605, anticorps DKFZp469A2113, anticorps COX17, anticorps Dopuin, anticorps COX17, cytochrome c oxidase copper chaperone, anticorps cytochrome c oxidase assembly protein 17, anticorps cytochrome c oxidase copper chaperone, anticorps COX17 cytochrome c oxidase copper chaperone, anticorps COX17 cytochrome c oxidase assembly homolog (S. cerevisiae), anticorps COX17 homolog, cytochrome c oxidase assembly protein (yeast), anticorps COX17 cytochrome c oxidase assembly homolog, anticorps COX17, anticorps Cox17, anticorps Tc00.1047053508153.994, anticorps Tb927.3.2650, anticorps PVX_111430, anticorps cox17
Sujet
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92 % amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.