Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CEND1 anticorps

CEND1 Reactivité: Humain, Souris, Rat ELISA, WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7248425
  • Antigène Voir toutes CEND1 Anticorps
    CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
    Reactivité
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 7
    • 1
    Lapin
    Clonalité
    • 6
    • 2
    Polyclonal
    Conjugué
    • 8
    Cet anticorp CEND1 est non-conjugé
    Application
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of human CEND1
    Isotype
    IgG
  • Indications d'application
    WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
    Autre désignation
    CEND1 (CEND1 Produits)
    Sujet
    BM88, also known as CEND1 (cell cycle exit and neuronal differentiation protein 1), is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.
    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 15 kDa

    UniProt
    Q8N111
Vous êtes ici:
Support technique